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reprocessing of cefotaxime sodium

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Cefotaxime | C16H17N5O7S2 | CID 5742673

Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis). DrugBank. Cefotaxime is a Cephalosporin Antibacterial. FDA Pharm Classes. View More... See also: Cefotaxime Sodium (has salt form). 1 Structures. 1.1 2D Structure. Structure Search. Get Image.

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DailyMed

Cefotaxime sodium overdosage has occurred in patients. Most cases have shown no overt toxicity. The most frequent reactions were elevations of BUN and creatinine. There is a risk of reversible encephalopathy in cases of administration of high doses of beta-lactam antibiotics including cefotaxime. No specific antidote exists.

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Electrocatalytic oxidation of low concentration cefotaxime sodium

In this research, Ti/SnO 2 –RuO 2 stable anode was successfully prepared by thermal decomposition method, and low concentration cefotaxime sodium (CFX) was degraded by green and sustainable electrocatalytic oxidation technology. The electrocatalytic activity and stability of the Ti/SnO 2 –RuO 2 coating electrode were …

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Cefotaxime Stock Solution

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Cefotaxime Sodium

taxime sodium may be administered in 50 to 100 mL of compat-ible diluent over 20 to 30 minutes by intermittent intravenous infusion or by continuous intravenous …

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DailyMed

Cefotaxime sodium overdosage has occurred in patients. Most cases have shown no overt toxicity. The most frequent reactions were elevations of BUN and creatinine. There is a risk of reversible encephalopathy in cases of administration of high doses of beta-lactam antibiotics including cefotaxime.

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DailyMed

Sterile cefotaxime sodium is a semisynthetic, broad spectrum cephalosporin antibiotic for parenteral administration. It is the sodium salt of 7-[2-(2-amino-4-thiazolyl) glyoxylamido]-3(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate 72 (Z)-(o-methyloxime), acetate (ester). Cefotaxime for Injection, USP …

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Cefotaxime : Drug class, mechanism of action, uses, dosage, …

Cefotaxime sodium contains approximately 51 mg (2.2 mEq) per each gram in parenteral form. The frozen solutions of cefotaxime sodium are additionally formulated with sodium hydrate as a buffer. In patients with conditions that may require sodium restriction (such as congestive heart failure, hypertension, and fluid retention), the sodium ...

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Tolerability, Safety, Pharmacokinetics and Drug Interaction of

Conclusions. Cefotaxime sodium–tazobactam sodium injection (6:1) was well-tolerated at doses of 0.47 to 4.68 g. The pharmacokinetics of cefotaxime and tazobactam were reported as linear over a dose range of 1.17–3.51 g.

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Cefotaxime. A review of its antibacterial activity, …

Cefotaxime is a new 'third generation' semisynthetic cephalosporin administered intravenously or intramuscularly. It has a broad spectrum of activity against Gram …

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Adsorption of cefotaxime sodium salt on polymer coated …

Cefotaxime sodium salt is a semi-synthetic broad spectrum cephalosporin indicated for the treatment of patients with serious infections caused by susceptible strains of the designated microorganisms in the various diseases, such as lower respiratory tract infections, genitourinary infections, septicemia, skin infections, intra-abdominal ...

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Cefotaxime Dosage Guide + Max Dose, Adjustments

Detailed Cefotaxime dosage information for adults and children. Includes dosages for Urinary Tract Infection, Sinusitis, Skin or Soft Tissue Infection and more; …

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CLAFORAN Sterile (cefotaxime for injection, USP) …

Cefotaxime sodium also demonstrates . in vitro activity against the following microorganisms . but the clinical significance is unknown.Cefotaxime sodium exhibits in vitro minimal inhibitory concentrations (MICs) of 8 mcg/mL or less against most (≥90%) strains of the following microorganisms; however, the

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Frontiers | Method Improving for Isolation and …

Cefotaxime sodium, as a raw material, was provided by the National Institutes for Food and Drug Control of the People's Republic of China. The purities of the cefotaxime dimer and trimer were >90.0%, as determined by HPLC, which were suitable for structural identification. 2.3 Reversed-Phase High-Pressure Liquid Chromatography …

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Highly efficient photoelectrocatalytic degradation of cefotaxime sodium

The MoSe 2 /TiO 2 NTs were used as both photoanode and catalyst in the degradation of cefotaxime sodium. • Cefotaxime sodium was removed efficiently by the MoSe 2 /TiO 2 NTs photoanode under low applied bias voltage. • A photoelectrocatalytic mechanism based on direct Z-scheme MoSe 2 /TiO 2 NTs heterojunction was proposed.

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From Jellylike Phase to Crystal: Effects of Solvent on Self …

Jellylike phase (JLP) is usually harmful to the process of crystallization. The special state of cefotaxime sodium (CTX) jellylike phase and its spontaneous transition to crystals is investigated in this paper. The crystals transformed from JLPs containing different solvents have distinct habits and forms. The solvent used in JLP formation and crystallization was …

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Cefotaxime 500mg, 1g Powder for solution for injection or …

Sodium intake: The sodium content of cefotaxime (2.09mmol/g) should be taken into account when prescribing to patients requiring sodium restriction. Clostridium difficile associated disease (e.g. pseudomembranous colitis): Cefotaxime may predispose patients to pseudomembranous colitis. Although any antibiotic may predispose to …

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Spectrophotometric method for the simultaneous …

Cefotaxime Sodium and Sulbactam Sodium exhibited linearity with absorbance in the range of 5-35 mcg ml1 and 2.5-17.5 mcg ml-1 at their respective selected wavelengths. Co-efficient of correlation were found …

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Investigation on the Spherical Crystallization Process of Cefotaxime Sodium

A new strategy incorporating the spherical agglomeration technique and the drowning-out crystallization process, by which the impurities can be efficiently removed, was performed and indicated that the purity and residual solvents of the experimental agglomers can meet the requirements for use. In order to obtain satisfied spherical agglomerated …

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A New Extractive Spectrophotometric Method for the …

2. cefotaxime sodium, cefotax ® vials labelled to contain 1000 mg cefotaxime sodium per vial ( EGYPTIAN INT. PHARMACEUTICAL INDUSTRIES CO. E.P.I.C.O. Egypt) 3. Eriochrome black T (EBT) was ...

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Study of the polymerized impurities in cefotaxime sodium …

They were cefotaxime sodium isomeric compounds and homologs generated during the production process or degradation products. CONCLUSION: The method can be applied in the identification and ...

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Cefotaxime sodium USP Reference Standard CAS 64485-93 …

Cefotaxime sodium United States Pharmacopeia (USP) Reference Standard; CAS Number: 6; Synonyms: Cefotaxime sodium salt,Cefotaxim sodium salt; find USP-1097909 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich

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PRODUCTION OF CEFOTAXIME AND NEW SODIUM SALTS

A process for the production of cefotaxime in acetone/water and its use in the production of a sodium salt of cefotaxime and a crystalline sodium salt of cefotaxime in form of rounded agglomerates and in form of needles. Full text links . Free to read at EPO

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Cefotaxime | Drugs | BNF | NICE

View cefotaxime information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, ... For intravenous infusion, manufacturer advises give reconstituted solution intermittently in Glucose 5% or Sodium Chloride 0.9%. Suggested volume 40–100 mL given over 20–60 minutes; incompatible with alkaline solutions. ...

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USP Monographs: Cefotaxime Sodium

in which C is the concentration, in mg per mL, of USP Cefotaxime Sodium RS in the Standard preparation; P is the designated content, in µg per mg, of cefotaxime (C 16 H 17 N 5 O 7 S 2) in USP Cefotaxime Sodium RS; W is the weight, in mg, of Cefotaxime Sodium taken to prepare the Assay preparation; and r U and r S are the cefotaxime …

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Cefotaxime (Cefotaxime for Injection): Side …

The empirical formula of Cefotaxime (cefotaxime for injection) Sodium is C 16 H 16 N 5 NaO 7 S 2, representing a molecular weight of 477.45. Cefotaxime (cefotaxime for injection) Sodium …

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Cefotaxime 1g powder for solution for injection vials

Cefotaxime sodium may be administered intravenously, by bolus injection or infusion, or intramuscularly. The dosage, route and frequency of administration should be determined by the severity of infection, the sensitivity of causative organisms and condition of the patient. Therapy may be initiated before the results of sensitivity tests are known.

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cefotaxime sodium | CAS#:6 | Chemsrc

Chemsrc provides cefotaxime sodium(CAS#:6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of cefotaxime sodium are included as well.

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(PDF) EVALUATION OF EFFICACY AND SAFETY OF CEFOTAXIME SODIUM …

A combination of cefotaxime and sulbactam (β-lactamase inhibitor) may be effective in combating resistance due to β-lactamase producing common respiratory pathogens.

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